Multifunctional ‘Dual Action’ Anti-Microbial Coatings For Implantable Medical Devices

RFT-260

Scientists at North Dakota State University have invented a unique ‘dual action’ anti-microbial polysiloxane coating that has the capability of exhibiting long-term antimicrobial activity on implantable medical devices. The coatings have a leachable silver-based antimicrobial domain in conjunction with a surface-bound contact active microbial agent - Quaternary Ammonium salt (QAS) that exhibits the two levels of antimicrobial protection. While the covalently bound QAS groups inhibits bio-film formation by microorganisms that come into contact with the coating prior to insertion of the devices into the body, the leachable antimicrobial agent inhibits bio-film formation by microorganisms in the vicinity of the device.

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File: rft-260.pdf

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Joy Goswami
Licensing Associate
NDSU Research Foundation
Fargo, North Dakota

(701) 231-7886 Work
(701) 231-6661 Fax
Email: jaideepgoswami@ndsurf.org

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