Antibacterial Siloxane Polymer Containing Tethered Levofloxacin
RFT-232
This invention pertains to the development of a polymer material that exhibits superior sustained release of therapeutic levels of the active antibiotic when compared to simple physical bending or doping technologies. The material is prepared by combining a powerful, broad spectrum antibiotic (Levofloxacin), tethered to a siloxane polymer. This invention can potentially be used to coat a variety of biomedically implanted devices for prevention of microbial infection.
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File: rft-232.pdf
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Jonathan L. Tolstedt
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NDSU Research Foundation
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